Inhalation anaesthetics: types, mechanism of action and adverse effects

Inhalational anesthetics have been used to induce and maintain general anaesthesia for more than 150 years. These anaesthetic agents are commonly in the surgical clinical practice solely as a conjugant with other anaesthetics. Since inhalational develop amnesia, loss of awareness, reduce reactions painful stimuli, they an essential part anaesthesia. The choice agent is based on procedure's duration type, patient characteristics, attending anaesthesiologist’s preferences, occasionally institutional protocols. medications administered through anesthetic circuit using special vaporizer. purpose this research review available information about inhalation anaesthetics: types, mechanism action adverse effects. Nitrous oxide one earliest while isoflurane, sevoflurane, desflurane three low-solubility anaesthetics sevoflurane several advantages over including rapid induction faster recovery after prolonged treatment. However, isoflurane can sometimes be effectively enough match times drugs. Inhalation work by suppressing inhibitory signals such chloride channels potassium enhancing excitatory acetylcholine, muscarinic nicotinic receptors, glutamate serotonin central nervous system. Certain side effects nausea, vomiting, malignant hyperthermia, post-operative cognitive impairment associated their use. More needed further enhance safety profile lead discovery new, safe